Once is not enough: clinical trials in sepsis

Indictment by Association: Once Is Not Enough

Early life infections with human bocavirus 1 (HBoV-1) are common, and the virus is readily detected in the upper respiratory tract, often during acute upper respiratory tract illness. Its etiological role in respiratory tract infections has been uncertain because of its presence in asymptomatic children and frequent concurrent detection of other respiratory viruses. Longitudinal cohort studies,...

HIV clinical trials are not enough.

"Once is Enough" in Radiometric Calibrations.

The successful development of an Optical Technology Division quality system for optical radiation measurement services has provided the opportunity to reconsider the existing calibration procedures to improve quality and reduce costs. We have instituted procedures in our calibration programs to eliminate uninformative repetitive measurements by concentrating our efforts on controlling and under...

Measurement of Weight in Clinical Trials: Is One Day Enough?

Background. Weight is typically measured on a single day in research studies. This practice assumes negligible day-to-day weight variability, although little evidence exists to support this assumption. We compared the precision of measuring weight on one versus two days among control participants in the Weight Loss Maintenance trial. Methods. Trained staff measured weight on two separate days a...

Not Enough Points Is Enough

Models of the untyped λ-calculus may be defined either as applicative structures satisfying a bunch of first order axioms, known as “λ-models”, or as (structures arising from) any reflexive object in a cartesian closed category (ccc, for brevity). These notions are tightly linked in the sense that: given a λ-model A, one may define a ccc in which A (the carrier set) is a reflexive object; conve...